Neuroprotection in glaucoma: recent advances and clinical translation
نویسندگان
چکیده
منابع مشابه
Neuroprotection for glaucoma: Requirements for clinical translation.
Within the field of glaucoma research, neuroprotection is defined as slowing the functional loss in glaucoma by a mechanism independent of lowering of intraocular pressure. There is currently a great potential for research surrounding neuroprotection as it relates to glaucoma. Anatomical targets for neuroprotection should focus on upstream rather than downstream factors, and could include any p...
متن کاملRecent advances in pharmacological neuroprotection
Treatment of brain ischaemic remains a challenging issue. During the last decade there has been much interest in the development of drugs with signifi cant neuroprotective effects against ischaemic injury in stroke patients. However, clinical trials have been disappointing as, so far, they all have failed to provide evidence for neuroprotection. Several reasons including lack of convincing expe...
متن کاملRecent advances in pharmacotherapy of glaucoma
Glaucoma is a slow progressive degeneration of the retinal ganglion cells (RGCs) and the optic nerve axons, leading to irreversible blindness if left undiagnosed and untreated. Although increased intraocular pressure is a major risk factor of glaucoma, other factors include increased glutamate levels, alterations in nitric oxide (NO) metabolism, vascular alterations and oxidative damage caused ...
متن کاملRecent advances in clinical practice RECENT ADVANCES IN COELIAC DISEASE
Correspondence to: Professor D A van Heel, Institute of Cell and Molecular Science, Barts and The London, Queen Mary’s School of Medicine and Dentistry, Turner St, London E1 2AD, UK; [email protected] _________________________ T he management of coeliac disease is an increasing part of a gastroenterologist’s workload. Recent prevalence studies suggest ,1% of the general UK population have po...
متن کاملRecent Advances in Hemophilia Gene Therapy
Heterogeneous loss of function mutations at F8 and F9 genes causes X-linked recessive bleeding disorders, hemophilia A (HA) and hemophilia B (HB), respectively. HA is clinically indistinguishable from HB and accounts for more than 80% of hemophilia cases; the former affects 1/5000 and the latter 1/25000 male births worldwide. In Iran, it is estimated that around 4300 HA and 900 HB patients are ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical & Experimental Ophthalmology
سال: 2018
ISSN: 1442-6404
DOI: 10.1111/ceo.13336